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Pimozide: Difference between revisions

From Pharmacopedia
[pending revision][pending revision]
Comprehensive categorization: +Diphenylbutylpiperidines
Category taxonomy (#23): retag to house-compliant neuroleptic categories
 
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[[Category:First-generation neuroleptics]]
[[Category:Antipsychotics / Neuroleptics]]
[[Category:First-Generation Antipsychotics (FGAs / Typicals)]]
[[Category:Neuroleptics]]
[[Category:Neuroleptics]]
[[Category:Diphenylbutylpiperidines]]
[[Category:Diphenylbutylpiperidines]]

Latest revision as of 14:41, 22 May 2026

Antipsychotic, Neuroleptic
Pimozide
Orap

Experience

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Problems

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Titration strategies

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Effects

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Interactions

Pharmacogenomic + mechanism interactions2 edges
Pharmacogenomic guideline recommendationsCPIC and Dutch Pharmacogenetics Working Group clinical guidelines
Phenotype:CYP2D6 poor metabolizer dose reduce 50 DPWG 60 / 100
DPWG guideline: Patients who are CYP2D6 intermediate metabolizers should be given no more than 80% of the standard maximum dose of pimozide while patients who are CYP2D6 poor metabolizers should be given no more than 50% of the standard maximum dose.
Phenotype:CYP2D6 intermediate metabolizer dose reduce 50 DPWG 60 / 100
DPWG guideline: Patients who are CYP2D6 intermediate metabolizers should be given no more than 80% of the standard maximum dose of pimozide while patients who are CYP2D6 poor metabolizers should be given no more than 50% of the standard maximum dose.

Patient experience

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Relevant Literature

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Pharmacy
Common uses
Classification(s)
Classes
Antipsychotic, Neuroleptic
Pharmacology
Purported mechanism
Diphenylbutylpiperidine D2 antagonist
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